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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1541ea127f654a1264728e455670a050b8ce38fb5c8c16dfec3e5e50e50b0f7e' 
  AND token = 'NqHCvpDLk+kgjnzpi+8MBEcGccoFCQ4DV6e+LdraZEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}