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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd8ddedcd71d25706e4cbeae95fa7179d68198d3acad914df47303e9b81db51f' 
  AND token = 'TNQPmW37iQlTAmbndQnahupfQA+jUDvNJkNvq4d0Yvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}