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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a67d043740e0f326dfb376c70d69b6960037b7ddcf396f3b9599673a15bf6a4' 
  AND token = 'yNHDKIWufgmhMSa4ljBbL6Re0XBDj5psv4NwNk8MgEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}