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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2f8d2c244bb7033834e0e1b3ad2e4949bf932687a0a80c980a051dfeeb5a3b' 
  AND token = 'py9jvktgKQnxrOjuIpIiLqHc8SnbZovZf4RN1RUnkY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}