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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b7b49fe0ed85f17b57ff111c7b260af3eace1ea5d80590eed601ae0b207da4' 
  AND token = 'YiF7oIwnmU+s4hnLe1V734hFyDRl5I8Mv1t7GkrMZxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}