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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493665a76e3afa6c2885e32ac88d44503c5b22974f75661a76d9367e79ba6fed' 
  AND token = 'IxVCWW54p8r2127glNrXebGZv0uKO+s0QS3prik6slQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}