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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859554190abbe7acb0259e8383c4e71ab793c0ccd6bea04872efc6c5e2ab25b4' 
  AND token = 'iTwh2piu2L0NwpcAF8X4+xcGAI8MozKUH58Md2pY900=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}