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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5196df5bd6c06e765f1a55a1adc706895d4360ac561c5912b84ba9c564a1faa' 
  AND token = 'BU/2N11NJweaa+MXVV3+UP8AFpPSEtSRRTUmMs22Jj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}