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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563f3a5e24156c799b85f6eea0de3727e560c94ab961f9ed24370e18999f79f0' 
  AND token = 'o3l93Gic6SxexIrgaEM6m2fC81OMCPdXTRQ2VV4Ph3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}