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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2f45054596772e0c699f8c427cde4a5e28341dbf32347d82c9ba5408bd1337' 
  AND token = 'PbUyNhxq8qk9gwbGOF0sO2/XqUtHfcHubn9xcbdqTRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}