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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2750721e9a782dd2a7e8bbce94cacd60b57b5b9e8c6e72cf19908cd8d062006' 
  AND token = 'ILSzfbVmEL1CKiZUe92rkdDX6BGj4HIwD0nYhPJ2GE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}