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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b158eeca7c7a72a53331feb41eddd63d02df109dfcd77ed5221689c0be9dde' 
  AND token = 'IizczbpvsSlSTCMeCg+0dbmdSnkIjBBJgsw8fIJtuNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}