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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4111282c5d6429456b8fc3454b7c43588cba81cde684de5b5699f51b1ecab616' 
  AND token = 'nTdRvEYkKKewK59+v+2DBJLrlXBkHhfUP9CQyXkPOQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}