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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0e7e6c2004866e74a790b695547d2365ebb8e041b20875b110b5196e2f9422' 
  AND token = '51OonzhaKQUaPFTdbVQxqKC5FdDNr3Js6VO+mYNjsQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}