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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6848209d45a87712ee90cd1febc3a105458cac179b904b605c356a1b5dcf0209' 
  AND token = 'zFs9heUx4MzG+t/ceh/4oTUPXDliyKeY1VRo0Pb4AzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}