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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c6b416b9a7e39db53dc6f416615e53a2b6046205a1c57749a3f08d121192c50' 
  AND token = 'pV/Eh2PIdl7ALrp6hTdf790T9c3azyglZqGiXtsgyAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}