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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503d02878ee9da08468d935b482e7e2ac426b40bb8156fa677c76e3fd1f05459' 
  AND token = '65AFPhZNOjzQb4Cr6KCh66Qqn8JzGn0xFJceh5bMaAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}