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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90c2ef2123a7684bf794c7f49c94b0c587995546f65ce1cb16a4c444ccceaef0' 
  AND token = 'ZwSWTgwA/KJcFaWe2TdEnZMrCXUzqtmYz3E6n+dI+sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}