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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bbd9836bdab74d00e00fddb098dfe3dd1e3255976c1baa9fdde94765012d489' 
  AND token = '1DM0OFlzvHB+8yyBat6wreWtrTLCjzjRLjLfU9iRk14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}