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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ad7101be96e5d0bf24af66c8a72680dd594b44ce2ccd384f5b9886d69b1c54' 
  AND token = 'HYJrs5aMQE93S4W/mXD5hJqlhCky/bCq0QBpIikZ4fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}