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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489ed394326dd0b46e25257688e8da3f29ce87b1721031ce21aee781ae95c857' 
  AND token = 'S84y1P2VtxJn3VtzOzCoi8TNWyXjWpJJog6WhpPwbGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}