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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2bcf7f0a41a2b8a6eafc6c8743a61019abd8ff031737603d14ec5c2400a72d6' 
  AND token = 'ka4VjNQ3fNEIa6dmmRgsbHiZq2HN70LpIUPGr5mdbWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}