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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd503eb29f0773abb026161f561e8c4c16966bf8623e1b3626d6c9b5ea1c07f5e' 
  AND token = 'N5IaksXXIIu1LnqEIWnb7nsQDwF+P4np2pXl8MyBS8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}