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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65bd66cc910fedefb55ebd855314cdb1e4fed2aac653fb7ee1869571b1ad4681' 
  AND token = 'hIpdPiEL+OaBow7pRc9PShrpXly0DA6tYq3sTTMwAz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}