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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e40304729e39c2e3d0908e961f9cf56b560b27fb900010a224d3dd9f6330f92' 
  AND token = 'Ql0QKFa1g4lgax5z67ladiu80pv8gOrqzWCo7zVzxKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}