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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4b203fd77017761cb1c5da784eb8f5ef637782a9590081ebb7ee078a379ed6' 
  AND token = 'nZdK6/8dfIZk+kSv24A6QJa+hmi8A1KP7MZ/KwzCBCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}