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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a74d5fd09a02cc38bd1be5021f9124713d2687124edfdc7373a9511d908bc013' 
  AND token = 'sJmB8GzhYyWB1C/d/c93x9heKMrE9Ne6ixG6GFyLGQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}