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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd8bfb2b56ffe9d883939896b127cf72ea039e9099ea9dc0bb2df40f9414f757' 
  AND token = 'qRsQzsYOfA3vRJLdWvEMO4CZhf0eNWB0TTbbSv+8WVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}