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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb59121db3059307be285742fb9b9dc71349f8d1fdf10574d86ae96fb4a5f26' 
  AND token = 'cPR2+1A1BpmaQRbJnFM4V5e2W5b0cVvt0ibI1ruxWuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}