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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7815fb3b6defe296c4c25b8c088aacc5adcdc793136b3cf4239094de8ac1438' 
  AND token = '+mafL1gVKoWONu8iCAnVC2OiwK6peunaWCBeOMKnIw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}