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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec8e3babbe58bd29f4a8dd6f51b1ea98514fb2f53a3b92c41c0ba38a6b3a8434' 
  AND token = 'LoeeJnNRtv+iBmqPnQT6s2XF4mfUU/cT8DByn2Emh64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}