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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd571e6505e3b119dae3e50b1abbcd137bcf4ac40feae3677c5b185619c4a07c1' 
  AND token = 'fn2OZRaV9e7orvSMYQ7LrYFHCfORHJyrVC5CO6J+hQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}