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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c91132a02f69e4b02439eda85ca3de24e1760776d711d60b6c32441822c905b' 
  AND token = 'waxEgRuQU2FRTXXZ/iBzyRH6kLaqRFTMkxgeOc+MiQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}