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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea2ba678c7c528308e014fb738254161e7b55d0d2c70fe78143c34a57e5b6868' 
  AND token = '+fk36Ts7ULE8JkN3AaBeeuCtxbzSb0rvrAuAblvyzR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}