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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5effba2588e377060480b3d2ab137e93a52df7f59a406d21ee82f1b9ac1632ca' 
  AND token = '26BVDPNLycCGAy0KF4yiX6nylBGurmZzxb3FWIwDPZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}