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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ddc61bd7a4bc071badae6c628ddcbe5b25a404a8a04de0bf4ac9e20e6ec3ca' 
  AND token = 'm5tN6PxhdRpmJ0QHFeqXnbJPfjTvhy2+XrgV9JYlNug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}