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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c62cdb7573d16a50dc85c149f1e7337462a6c477fb2f467dede342c5eb411d' 
  AND token = 'aY/lPag2KOA5RvIyX+cczCnTf6T0ESZeLyPlcbTUmiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}