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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb221dbf0b99c9e9e175413663a31dfeb561d4c95c6a509722fab15e987ceab8' 
  AND token = 'MtF0+fKG46OexzMcJXQcYVz11TnnFzG772uCiFQAlJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}