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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2adccd6c66613402373881b781c7f5aa7cb3c5cce6fac8de0a9388981184e9be' 
  AND token = '1+n6eTXiqLlL8ijb9OXq/yXqfVnWFPa1Cqo8Ny/tyVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}