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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33368cffecf963e44c07ca0c89bf818955747e9254f99aaac5c814a42488d811' 
  AND token = '3iiB2kbseW7tqK1DLK+WgnGOUHF63xCh+LvzkKoB2L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}