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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd331f18def5a12a1320fd7f7aae31c3d363be34a7676812e27e07640e29666d' 
  AND token = 'EPzUhX5CnUXeMzdxwcgqE3ebLKlCWgGy3dD2p+6VIg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}