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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d098e2bc7d86898b1307211fc815f931fe3e9ebcf35af7eb74fcd3453656e4' 
  AND token = 'Dkk0VK6gVSLb+rDoD7cNVIOwr2Ws1fZacrkyQqeqBgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}