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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e1fe25a337d25bc104ef2f4f4b6a41f30f96b2cb9d748bf484225be30926d3' 
  AND token = 'XJUPC0gPj8qJRNo7PMlAy9MDuxKucrSVEXaZZuNfPfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}