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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4fa531c8b49a56c60b8d9100e459c07732568e2804086b298d518f388215803' 
  AND token = 'DEiuAga92rllGwHwY76mzQGLWfcA1397UKGsrT5sW9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}