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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ec2c7ba86fd20a98106cfb84280b12e09b4a4626a57bf5fc8ada2b67106a0a' 
  AND token = '32i9bilq/edJsmY+nOeMioFMd23aV10yRT7T8TM8Rxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}