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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b709218a30742fea230de44f6c9844b3a6c063fcd5b34569df5feda362dfe33c' 
  AND token = 'u4jMDFIH6FBW2PKCXpuGmfCCDYc+yP8N1nvdPrsaC2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}