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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a6aea03486ef1dbfffdb843e2b3d9c9f6e99436dc18e09996f88807742208aa' 
  AND token = 'aUUV7lapbEG38XVrGc5xli1eJwzWxP+pRbM5Fk/xdKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}