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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82a0bc57f82fe89500ab8f67a921807573f71a95def039fa28be5a59fa8c27c6' 
  AND token = 'HxvFXg+vwXtQNaZTc+RIeOlubUGnphe/TSEmo3Dyfv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}