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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080fe8ed1e6aa1d176a9ea1d20914cb374a00728965e59e65dc78642230e1b62' 
  AND token = 'RhzeDlfjVD9lw895g12zC6IuMU7Ccg+RI3v2SKLr2CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}