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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f7785b5b74d58bacb6c5a0aa6f7861782934b2e95c7ef585f4538cec3f6739a' 
  AND token = '3edQjXNk7+J1zDr1Vjm8qkrVKP5PrI2hc7ifLm6rlHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}